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Goal: Maximize sperm production while on testosterone therapy Approach: HCG 500 IU subcutaneously every other day Consider adding FSH or HMG if response insufficient after 3 months Semen analysis at baseline, 3 months, and 6 months Timeline: Initial testosterone response: 2-4 weeks Sperm appearance: 3-4 months Significant count improvement: 4-6 months If conception remains the urgent priority, discontinuing TRT while increasing HCG to 3000 IU every other day accelerates recovery
Tummers B, Green DR
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Studies have shown that semaglutide can reduce appetite and food cravings, leading to weight loss as well
The manufacturer recommends dosage reduction in patients receiving potent cytochrome CYP3A4 inhibitors such as erythromycin (see Dosage)
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