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Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis

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Its Phase 3 GLORY-2 trial showed 20.1% weight loss at 60 weeks, and the DREAMS-3 trial demonstrated head-to-head superiority over semaglutide 1 mg

The 2.5 mg dose is below the therapeutic range for weight management

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One-to-one pair matching between patients who received semaglutide and those who received dulaglutide was performed using greedy nearest neighbor matching with calipers of width equal to 0.1 SD of the logit of the PS