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Mechanisms of Drug Entry into Human Milk The amount of drug excreted into milk depends on a number of kinetic factors: 1) the lipid solubility of the drug, 2) the molecular size of the drug, 3) the blood level attained in the maternal circulation, 4) protein binding in the maternal circulation, 5) oral bioavailability in the infant, and the mother, and 6) the half-life in the maternal and infant's plasma compartments
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Step 5: Monitor your response If you decide to continue using the vial after a storage incident, pay close attention to your body response over the next one to two weeks
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