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This work was supported by grants from the National Key Research and Development Program (2022YFC2304500), the National Natural Science Foundation of China (82270631), the ECCM Program of the Clinical Research Center of Shandong University (2021SDUCRCB006), and the Young Taishan Scholars (tsqn202103169)

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Gyimesi M, Okolicsanyi RK, Haupt LM (2024) Beyond amyloid and tau: rethinking Alzheimers disease through less explored avenues

and the FI group up-regulated 28 differential metabolites and down-regulated 32 differential metabolites relative to the GSH group

Most protocols recommend splitting the difference at 28 days maximum