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The gutbrain axis and its health connections The gutbrain axis (GBA) is a complex, bidirectional communication network, which encompasses the gut, the CNS, and several other systems including the peripheral nervous system (PNS), autonomic nervous system (ANS), ENS and the hypothalamic-pituitary-adrenal (HPA) axis 30

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In addition to stimulating insulin secretion, pharmacologic concentrations of GLP-1 (and GLP-1 receptor agonists) inhibit gastric emptying, and suppress glucagon secretion

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