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Therefore, the SGLT2-i induced elevated ANG II levels could act through AT2R resulting in vasodilation, sodium excretion, antiproliferative and anti-inflammation effects (51)

The trial was halted after the original commercial sponsor inappropriately released preliminary findings of a confidential early analysis

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El ensayo STEP 1 demostr una prdida de peso promedio de 14.9% del peso corporal inicial a las 68 semanas, comparado con 2.4% en el grupo placebo

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