Sustained increases in iron or decreases in GSH suppress GPX4 levels thereby compromising cellular antioxidant defenses
(PubMed) McNeil JJ, Robman L, Tikellis G, Sinclair MI, McCarty CA, Taylor HR
doi: 10.1007/BF00609183 8 CantinA
Sonntag, Anna Csiszar, Raphael de Cabo, Luigi Ferrucci, Zoltan Ungvari, Diverse Roles of Growth Hormone and Insulin-Like Growth Factor-1 in Mammalian Aging: Progress and Controversies, The Journals of Gerontology: Series A, Volume 67A, Issue 6, June 2012, Pages 587598, Mario Thevis (13 December 2010)
A compound that is clean enough for a binding assay is not automatically clean enough for a quantitative cell-based readout where a co-eluting impurity could carry activity of its own
Vcut enerji iin yalar daha verimli kullandnda, kaslardaki eker depolar daha yava tkenir