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doi:10.1073/pnas.1513973112 Underhill SM et al (2020): Amphetamine Stimulates Endocytosis of the Norepinephrine and Neuronal Glutamate Transporters in Cultured Locus Coeruleus Neurons

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5e, there was negligible COL II staining in the control group and PMI hydrogel-treated group, and increased expression of COL II was detected when TA or KGN was introduced into the hydrogel matrix

Important cautions: History of medullary thyroid carcinoma (MTC) or MEN2 , pancreatitis , gallbladder disease, severe GI disorders, certain drug interactions, and pregnancy/breastfeeding considerations

This dangerous combination can rapidly precipitate acute heart failure, fatal pulmonary edema, cardiac arrest, and death (Ebert 2026, Medical Advisory Board 2026a, Medical Advisory Board 2026b)