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semaglutide improves hepatic inflammation, fibrosis, and immune remodeling through actions on Glp1r+ pericentral liver sinusoidal ECs (LSECs) independent of changes in body weight (BW), the team reported
Adjustment for age, parity, ethnicity, income, occupation, education and preexisting comorbidity did not alter the findings substantially (adjusted HR 0.96 [95% CI 0.83-1.12]), nor did the sensitivity analyses produce results that supported a significant association
The findings indicated that there was a significant difference in GST protein levels among MCI and AD patients after a year of observation, with alterations in GST showing a negative correlation with cognitive function decline
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