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Higher doses tended to result in more weight loss compared to placebo

Therefore, clinical selection must be highly individualized: tirzepatide should be prioritized for patients requiring maximal weight and glycemic improvements, whereas semaglutide is currently optimal for those requiring proven cardiovascular event reduction

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We included adults with type 2 diabetes who were prescribed a GLP-1 receptor agonist, SGLT2 inhibitor, or both between January 1, 2015, and June 29, 2024

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The authors are quick to say this is not an anti-aging drug