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Pickett and Lu, 1989
Transgenic mice lacking LEC-specific MHC-II expression displayed attenuated heterotopic tumor growth, accompanied by elevated numbers of tumor-specific CD8 + and effector CD4 + T cells, as well as reduced numbers of T regulatory CD4 + cells in the TME (104)
The role of mitochondrial dynamics and mitophagy in carcinogenesis, metastasis and therapy
Not approved for human consumption
doi: 10.1016/s0928-4257(99)00119-9
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Marchadier E, Oates ME, Fang H, Donoghue PCJ, Hetherington AM, Gough J
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