While this may not be applicable to all patients, for those who have achieved sufficient weight loss, gradually extending the injection interval is a promising strategy to reduce the burden while maintaining the effects, the research team stated
doi: 10.1038/s41467-018-06812-y 52 SmithALWhitehallJCBradshawCGayDRobertsonFBlainAPet al
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[7] While kava appears safe in traditional South Pacific use, caution is advised, especially during pregnancy, for people with preexisting liver conditions, or when combined with alcohol consumption, prescription drugs or dietary supplements