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To form an active G protein-coupled complex, HA-GLP-2R(1490)-LgBiT-TEV-OMBP-MBP was co-expressed with a dominant-negative bovine G s (DNG s ), rat G1-HiBiT and bovine G2 in Sf 9 insect cells
H.WangZ.FanY.LevisonB.HazenJ
However, clinical data confirms that weight loss is significantly slower with microdosing compared to standard therapeutic doses, often resulting in much less total weight loss over the same period
This results in an IGF-1 deficiency and high GH levels in the range seen in acromegaly patients
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