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In naturally aged mice, the renal function improvements were statistically significant but more modest a pattern consistent with the lower but still meaningful senescent cell burden in normal aging

10.1002/adma.202100599 65 WangX.ZhongX.LiJ.LiuZ.ChengL

Moreover, the peptide demonstrated high toxicity and lacked selectivity

The ROS generation was detected with a Leica fluorescence microscope (Leica DM6000B) using Leica LAS X software, and quantitative analysis was performed with ImageJ software (version 1.60