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These immunomodulatory effects complement their metabolic actions, contributing to improved liver outcomes and systemic benefits

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One difference between their model and the one reported here is that deletion of Gclc is induced in hepatocytes of adult mice (which are slowly proliferating), compared to theirs, where deletion of Gclc occurred in hepatocytes of growing animals (which are rapidly proliferating)

The mPFC voxel was placed medially, anterior to the genu of the corpus callosum, and aligned with the anterior-to-posterior commissure line