Key education points include: GLP-1s are tools, not cures
While the top of TM6 and ECL3 could not be confidently modelled for the exendin-4 complex, the portion of TM6 and TM7 that were modelled, along with the weak density corresponding to ECL3 supports a backbone conformation more similar to GLP-1 and oxyntomodulin bound receptors, rather than exendin-P5, albeit it is likely that this region is more conformationally dynamic
Sitagliptin is contraindicated in patients with a history of hypersensitivity reactions to sitagliptin
We treat metabolic and hormonal conditions alongside weight loss
Your busy schedule shouldn't get in the way of your weight care, we can help manage your program securely in the Direct Health app, reducing the amount of in-person visits needed to keep you on track with your goals
3 There are also strict guidelines for who qualifies for these medications, and theres a spectrum of little-talked-about weight-loss medications available on the market that arent GLP-1s