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GSH augmentation deserves investigation as a beneficial therapeutic approach for not only PD but also numerous other CNS disorders for which GSH deficiency and GSH-related enzyme deficits have been documented (multiple sclerosis, 25,26 autism, 2729 Alzheimers disease, 30,31 schizophrenia, 32,33 and bipolar disease 34 )
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Targeted mRNA decay by RNA binding protein AUF1 regulates adult muscle stem cell fate, promoting skeletal muscle integrity
doi: 10.1001/jamaneurol.2022.2977 37 FoxJTTullidgeGM
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These two research directions overlap in the literature but represent distinct lines of inquiry, each rooted in a different aspect of the peptides mechanism
