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Its main role is to neutralize free radicals, which are mainly responsible for cell damage and related aging
This study further demonstrated that exendin-4 treatment additionally reduced the presence of key inflammatory molecules, including TNF-alpha, interleukin 1 beta (IL-1beta), and IL-6, in mice livers [46], providing evidence for potential GLP-1 treatment for inflammation related to steatohepatitis
Subcutaneous injections resolved the oral bioavailability issues of incretins while the short half-life barrier was resolved when researchers identified other animals that also produce similar GLP-1 molecules [25]
doi: 10.1016/j.jacl.2025.08.022 131 ChuJZhangHWuYHuangYZhuTZhouZet al