The abundance of acquired immune cells (helper T cells and NK cells) was found to be negatively correlated with MAN1B1 expression by single-sample gene set enrichment analysis (ssGSEA), whereas the abundance of innate immune cells (Th2 cells, macrophages, Th1 cells, neutrophils) was positively correlated with MAN1B1 expression ( 2.1.3 COL6A1 In recent years, it has been found that there is a significant effect of TME on the growth and spread of tumor cells, in which extracellular matrix (ECM) is an important component of TME, regulating the growth, invasion, apoptosis, drug resistance and metastasis of tumor cell ( 2.1.4 NXPH4 Neurexophilin 4 (NXPH4) is a synaptic secretory protein belonging to the NXPH family
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