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This detoxification reaction is carried out by the glyoxalase system
It can cause excessive flatulence, and even reduce nutrient absorption
The amount of weight loss achieved with Orlistat varies, with clinical trials over a one year period showing between 35% and 55% of subjects decreasing body mass by 5%, and 15% to 25% achieving at least 10% decrease
Lingvay I, Catarig AM, Frias JP, Kumar H, Lausvig NL, le Roux CW, Thielke D, Viljoen A, McCrimmon RJ
Everything in Protocol 1, plus: Probiotic: 10-30 billion CFUs daily (multi-strain with Lactobacillus and Bifidobacterium) Ginger extract: 250 mg four times daily (or 1-2 grams raw ginger) Vitamin B6: 10-25 mg daily for nausea Electrolytes: Sodium, potassium, and magnesium if experiencing dizziness or dehydration Expected benefits: Reduced nausea, more regular bowel movements, less bloating, better tolerance of the medication especially during the early side effect period
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