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Preclinical studies have demonstrated that GLP-1 receptor agonists can attenuate nicotine self-administration behaviors and reinstatement in rodents, suggesting a potential role in preventing relapse

Presented for research literature review only Caccuri AM et al

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Trends in Andrology and Sexual Medicine

Theyre present in the gut, but also in the brains reward-processing regions, the same pathways that govern cravings

Negative controls included INS-1 832/3 SNAP/FLAG-hGLP-1R cell lysates incubated with empty Sepharose beads (SigmaAldrich) and INS-1 832/3 cell lysates (not expressing the tagged receptor) incubated with anti-FLAG M2 beads