HUBERMAN: Now we know that as we age, the amount of melatonin that we release is decreased such that if you look in babies and teens, et cetera, melatonin levels are very, very high compared to people of middle age and of elderly age
Speaking of the liver, you may also have heard of NAC, a popular liver health supplement
Overnight delivery is available in some cases, too
Topical Administration (Most Common) The most widely used approach is topical application via DMSO (dimethyl sulfoxide): Dissolve 3-5mg Dihexa in a few drops of DMSO Apply to forearm skin (DMSO acts as a carrier to drive the peptide through the skin) DMSO concentration: ~20-30% in the solution Pros: Effective absorption, avoids injection Cons: DMSO has a strong garlic-like odor that can transfer to breath/skin Starting Dose Begin at 1-3mg topically to assess response Work up to 3-5mg if tolerating well Cycling Protocol Dihexa appears to have lasting effects that persist after stopping likely due to synaptogenesis (new connections don't disappear when you stop)
This allows for nearly 100% absorption
User 7 started using 1mg daily for the acute phase following major foot surgery, planning to reduce afterward