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SPI-1005 is selective to the cellular hardware of the inner earspecifically the high-metabolism cochlear machinery that processes acoustic signaling
This preserves the natural pulsatile release pattern and negative feedback mechanisms, typically resulting in a safer side effect profile (Prakash & Bhatt, 2013, Indian Journal of Endocrinology and Metabolism )
Clinical amelioration achieved in episodic dyspnea, wheezing and medication was reported with the same behavior pattern observed for lung function tests (data not shown)
The regulatory agency seized thousands of units that had entered the market
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