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The SOD1 gene, located on Hsa21, is found overexpressed in the thymus and lymphoblastoid cell transcriptome maps analyzed in this work, with a consistent expression ratio of 3:2, confirming the previous literature ( The analysis of three transcriptome maps reported the overexpression of the genes encoding for the metallothionein family, a group of small proteins that chelate metal ions through metal-thiolate bonds with cysteine residues and that have a role in cellular zinc homeostasis and metal detoxification
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Gobburu JV, et al
Its levels in the body can be reduced due to aging, poor diet, chronic illness, or exposure to environmental toxins
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