PT-141 is a synthetic cyclic heptapeptide melanocortin receptor agonist (alpha-MSH analog)
$59.00 Availability: 116 in stock (can be backordered) Availability: 116 in stock (can be backordered) *Research chemicals are chemical substances used by scientists for medical and scientific research purposes only
The compound did not affect fasting glucose, insulin, HbA1c, IGF-1, cortisol, thyroid hormones, or liver enzymes (Thompson et al., 2004)
The defining mechanism reported for TB-500 in the literature is its interaction with actin , a fundamental protein of the cell cytoskeleton
Mucosal absorption formats
Biological Activities Observed in Studies Selective inhibition of nicotinamide N-methyltransferase (NNMT) Increased intracellular nicotinamide availability Modulation of NAD metabolic pathways Enhanced mitochondrial energy metabolism in experimental models Reduced adipocyte hypertrophy in preclinical studies Altered lipid metabolism and fatty acid utilization Investigation of cellular methylation pathways Potential influence on metabolic flexibility Evaluation of adipose tissue remodeling mechanisms Research applications in aging and regenerative biology Current evidence remains limited, and further well-controlled clinical studies are required to establish long-term efficacy and safety in humans