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Importantly, AOD9604 achieved these effects without activating the growth-promoting pathways that full-length growth hormone uses, which is why it doesnt cause the unwanted side effects of growth hormone therapy such as insulin resistance or abnormal growth
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Pharmaceuticals 15: 844 (2022) Schleiff M, Chen J, Yang J, Sommers C, Shen X, Rodriguez J, Keire D, Shu Q
however, they may involve the activation of molecules such as FRS1/2, ERK1/2, and STAT3 [65]
e-Pub 1987
Calcium Channel Blockers (CCBs) Mechanism: Block L-type calcium channels vascular smooth muscle relaxation peripheral resistance Types & Examples: Dihydropyridines: Amlodipine, Nifedipine more vasodilatory Non-dihydropyridines: Verapamil, Diltiazem also heart rate Key Points: Good for isolated systolic hypertension, angina 4
