Lacidipine inhibits the activation of the transcription factor NF-kappaB and the expression of adhesion molecules induced by pro-oxidant signals on endothelial cells
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Tesamorelin stands out with a robust clinical corpus including pivotal phase 3 trials on over 800 patients (HIV lipodystrophy indication), with 52-week data documenting a significant reduction in visceral fat (visceral adipose tissue, VAT) and improved lipid parameters
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Real-time PCR was performed using an S1000 PCR instrument (Bio-Rad, Hercules, CA, USA) to quantify gene expression
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) and dimethyl sulfoxide (DMSO) were acquired from MP Biomedicals (Illkirch, France)