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MC1R in peripheral melanocytes driving melanogenesis, and central MC3R/MC4R in hypothalamic and limbic circuits driving sexual behaviour
Generally well-tolerated with no serious side effects reported in studies
Common side effects include nausea, constipation, and difficulty meeting nutritional needs due to appetite suppression
Oncogene 36 (29), 41354149
In laboratory settings, this combination is commonly examined for
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