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aumenta el riesgo de fracturas, en especial de extremidades superiores y el riesgo de infarto agudo de miocardio, aunque estudios recientes entregan resultados tranquilizadores sobre este ltimo aspecto
Anandhan A, Dodson M, Shakya A, Chen J, Liu P, Wei Y, et al
"Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial." JAMA , 2021
Additional baseline and clinical features are available in Table 1a & b
Conversely, the hormone insulin directly lowers blood glucose levels by promoting the transfer of blood sugar into the cells
These cases highlight the central challenge: ensuring exceptional safety and tolerability for long-term use
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