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Finn PF, Dice JF

FIGURE 8 Atherosclerosis, a chronic inflammatory disease, may be an ideal environment for the high viral replication capabilities of SARS-CoV-2 in human cells, enhancing hyper-inflammation secondary to immune system dysregulation (Figure 9) that leads to adverse outcomes, as shown in patients with cardiovascular risk factors (258, 259)

Another important protein involved in folate transport in the adult human is the FOLR1 (folate receptor 1) encoded receptor protein

Glutathione depletion induced by c-Myc downregulation triggers apoptosis on treatment with alkylating agents