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Acknowledgments The authors thank the co-workers of the Institute of Animal Nutrition and the co-workers of the experimental station of the Friedrich-Loeffler-Institut in Braunschweig for their great support, as well as all other members of the MitoCow team

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Peer review Peer review information Nature Reviews Nephrology thanks Lin Sun, Mattias Carlstrom and the other, anonymous, reviewer(s) for their contribution to the peer review of this work