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47%) and constituted 32.7% of the total liraglutide psychiatric adverse events reported (48/147

In models of heart failure (HF), GLP-1 RAs have been observed to alter energy substrate utilization, alleviate myocardial and endothelial inflammation, mitigate oxidative stress, and antagonize myocardial remodeling [14]

doi:10.1016/j.cmet.2012.05.012 43

The protein encoded by the isoform 3 mRNA lacks 227 amino acids that are present in the central region of the protein encoded by the isoform 1 mRNA

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Evidence remains incomplete, so treatment plans should be individualized