The subjective experience was better even if the long-term weight outcome was similar
There is no need for daily maintenance dosing, cycling, or loading
In all, persistent tissue injury provokes chronic inflammation and an increase of pro-fibrotic factors, such as TGF-1, ROS, PAI-1, ROCK, TNF, and TIMPs, which induce the phenotype transformation of precursor cells to myofibroblasts
It took several weeks before I was able to bicycle (a favourite Dutch hobby) more than a few kilometres, but nowadays, I only have faint memories of how sick I really was
The skins structure also suffers under the strain of rapid weight loss, often resulting in sagging and loss of elasticity
One of the key players in eczema-prone skin is a yeast called Malassezia