Short-acting GLP-1RAs generally lower postprandial blood glucose by delaying gastric emptying time, while long-acting GLP-1RAs reduce fasting glucagon or increase fasting insulin concentration [37]
Addressing polypharmacy and comorbidities If you take several medications, have them all reviewed before starting GLP-1 therapy
doi: 10.1016/j.bbrc.2017.06.031, 104 NauckM
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Off-label use may seem dangerous, but its only done when a drug has been shown to be effective in medical literature and the class of drugs already has FDA approval for another purpose