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Helps in the detoxification of the liver and offers an alternative route of metabolism in acetaminophen poisoning

Heerspink HJ, Sattar N, Pavo I, Haupt A, Duffin KL, Yang Z, et al

However, the overall effect of hepatocyte-specific EGFR deletion on steatosis and gene signatures associated with NAFLD was much weaker compared to systemic pharmacological inhibition observed in our previous study

The 2-oxoacid dehydrogenase complexes in mitochondria can produce superoxide/hydrogen peroxide at much higher rates than complex I

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