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doi: 10.1111/hel.12881 94 WroblewskiLEChoiEPetersenCDelgadoAGPiazueloMBRomero-GalloJet al

In cancer, however, DDR exerts a paradoxical influence: while repair deficiencies promote mutagenesis and tumorigenesis, restoration or hyperactivation of DDR pathways in established tumors fosters resistance by enabling efficient repair of therapy-induced DNA damage

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This article delves into the biological roles of these peptides, their therapeutic applications, and how they may support injury recovery

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2010, Dec;35(12):66975