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Hence, mTORC1 sense glutamine availability in both directions: when glutamine is available, mTORC1 is activated via -ketoglutarate production

[1] Particular concerns with multi-dose vials include dosing errors (confusion between mg, mL, or units) and contamination from repeated access

doi: 10.1111/j.1530-0277.2011.01487.x 87 VermaVKLiHWangRHirsovaPMushrefMLiuYet al

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After reconstitution, preparations are generally stored under refrigerated laboratory conditions between 2C and 8C, provided this is consistent with institutional procedures and available product documentation

They also play a crucial role in modulating lipid metabolism, reducing hepatic steatosis, and improving liver histology, thereby addressing the underlying pathophysiology of metabolic syndromes (Qi et al., 2024)