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doi:10.1021/jf504383g
Alpha-1 and alpha-2 receptor stimulation causes peripheral vasoconstriction, increases blood pressure, and reduces mucosal and vascular edema
10.3390/ani12141824 28
While the body has several antioxidant defense mechanisms, too many free radicals can overwhelm our body and (among other things) impact gene expression, which could lead to inflammation
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That selectivity is why it kept appearing in later research
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