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These GLP-1 medications have become incredibly popular, because they are effective
In the absence of comorbidities or identifiable risk factors, semaglutide-induced ischemic colitis appears the likely etiology
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Special considerations : For patients taking tirzepatide (Mounjaro, Zepbound), note that it may reduce the effectiveness of oral contraceptives during initiation and dose escalation
However, as GLP-1 agonists are more frequently used this is something that needs further research and should be considered in cases of otherwise unexplained delayed gastric emptying.
GLP-1 medications, however, can help many people lose a significant amount of weight and lower their risks for these other conditions
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