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4.4 Pharmacokinetics and bioavailability As described above, BBR has a low bioavailability and poor oral absorption, at less than 1% across various in vivo and in vitro studies [60]
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Some studies reported up to a 30% risk reduction a signal too strong to ignore
There are indications of effects on certain biomarkers, but results are context-dependent
Biggers RD: Self-administration of dimethyl sulfoxide (dmso) for interstitial cystitis
That being said, an alternative measure was used by the research team that assessed motor function by grading the toe and heel foot print characteristic on a scale from 0-4, with 0 defined as no print, non functional, and 4 defined as complete print, near normal functioning [2]
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