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If an adverse effect, or even the inconvenience, of a particular therapy outweighs the benefits for the patient, then it might not be worthwhile to include it in a management strategy

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& Muller, W

Cureus 10 , e3178 (2018)

Correspondingly, we found that the NAC treatment largely increased the number of surviving SGNs in the peroxynitrite + NAC group compared with the peroxynitrite-only group, as well as in the peroxynitrite + gpx1 / + NAC group compared with the peroxynitrite + gpx1 / group (Figure 6D)