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This structure limits upside but cushions downside
Always patch-test new formulations
Discontinuation rates were substantially reduced to 18.8% (95% CI 18.6, 19.0) at 1 year and 36.8% (95% CI 36.5, 37.1) at 3 years when using a grace period of 180 days, and to 28.8% (95% CI 28.5, 29.1) at 3 years when using a grace period of 365 days
Neurology 49, 597606
However, three currently approved ADCs have pH-sensitive linkers
The study aimed to establish a method that could reliably detect sequence fragments, confirm modification sites, and generate reproducible peptide maps
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