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They described treatment selection as individualized according to comorbidity burden, tolerability, and weight-loss goals

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3): (1) comprehensive elucidation of molecular mechanisms underlying the antitumor effects, specifically utilizing advanced methodologies including single-cell sequencing and multi-omics approaches [18, 88, 89, 91, 92, 126]

Despite their advantages, peptides face ongoing limitations including stability challenges, delivery constraints, and higher costs compared to traditional pharmaceuticals

Conformational restriction in a series of GPR119 agonists: differences in pharmacology between mouse and human