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Your doctor will discuss strategies to manage any side effects

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Matrix metalloproteinase-9 (MMP-9), a member of zinc- and calcium-dependent proteolytic enzymes family,(Rosell and Lo, 2008) is widely distributed in multiple cell types such as neurons, astrocytes, microglia, and endothelial cells, across the central nervous system (CNS) (Kawasaki et al., 2008

Immediate medical attention is required if thirst is accompanied by any of the following: Severe or persistent vomiting or diarrhoea leading to inability to maintain hydration Signs of dehydration such as dizziness, reduced urine output, dark-coloured urine, or dry mucous membranes Symptoms suggestive of hypoglycaemia (blood glucose below 4 mmol/L) that do not resolve with standard treatment Severe abdominal pain, which may indicate pancreatitisa rare but serious adverse effect of GLP-1 receptor agonists Symptoms of DKA, including rapid breathing, fruity breath odour, confusion, or loss of consciousness If pancreatitis is suspected (severe, persistent abdominal pain, possibly radiating to the back), stop taking semaglutide and seek urgent medical assessment

Ikizler TA, Flakoll PJ, Parker RA, Hakim RM

The video consult was straightforward