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Patients were required to have evidence of a GLP-1 RA prescription fill and documented reason for discontinuation from a GLP-1 RA
We confirmed this observation in more independent data sets on melanoma and colorectal cancer (Figure 7B)
The damage it causes is often permanent, and early symptoms can be subtle
B vitamins decreased the number of M1 macrophages expressing the Ca1.2 channel and increased the number of M2 macrophages expressing the same channel, suggesting a role in M1/M2 transition post-PNI
It's a classic case of two different tools affecting the same location for two different reasons
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