It's worth bringing a few signals into the clinic, including irregular or absent periods, signs of hormone imbalance that disrupt daily life, difficulty losing weight despite consistent effort, or concerns about fertility now or in the future
Before taking a supplement, get the go-ahead from your clinician
GLP-1 can stimulate pancreatic -cells to release insulin.236,237 Insulin not only directly lowers blood glucose levels but also further inhibits glucagon secretion from -cells through a feedback mechanism.238 The high concentration of insulin in the local pancreatic environment creates a negative feedback effect, reducing the amount of glucagon secreted by -cells.234 Additionally, GLP-1 can reduce blood glucose production by delaying gastric emptying and decreasing appetite, which also contributes to overall blood glucose control.239,240 In summary, GLP-1 lowers blood glucose levels and inhibits glucagon secretion through direct action on -cells, promotion of insulin secretion, and regulation of gastrointestinal activity.241 GLP-1R is expressed not only on -cells and -cells but also on -cells in the pancreatic islets.242 -cells primarily secrete somatostatin, which is an important regulatory hormone.242 The expression of GLP-1R on -cells helps to inhibit the secretion of glucagon.242 When GLP-1 binds to GLP-1R on -cells, it activates these cells and promotes the secretion of somatostatin.243 Somatostatin is a potent inhibitory hormone that affects the surrounding -cells and -cells
The results were highly encouraging, with participants experiencing significant weight loss
Action: Annual comprehensive labs
Clinical Update 5/05/2020 CBD for Osteoarthritis Pain A recent study, conducted in dogs, showed promise for CBD in reducing pain and inflammation due to osteoarthritis (pain due to worn joints)
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