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The Case for Direct Switch For patients who are well-tolerating semaglutide and switching primarily for efficacy, a direct switch on the next injection date is the most common clinical practice
There are also instances where patients come in on a circumstantial basis if they: need an immune boost, want a hangover cure, are feeling under the weather, or are preparing for, or recovering from, a big athletic event like a marathon or other athletic competition
Individuals with thyroid disease, or taking thyroid hormone replacement should consult a physician prior to using L-carnitine
The practical reality: neither medication is clearly "gentler" for everyone