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The absorption mechanism is too precise and the margin for error is too narrow

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Absolute contraindications Medullary thyroid cancer MEN-2 Pregnancy or breastfeeding Prior severe allergic reaction to GLP-1 medications Conditions requiring extra caution Gastroparesis or delayed gastric emptying History of pancreatitis Advanced diabetic retinopathy Use alongside medications that increase hypoglycemia risk These and a few other situations require individualized assessment, which is why specialty endocrine care matters

14 Treatment discontinuation reflects a combination of factors, including gastrointestinal tolerability issues and other safety concerns, 15 financial cost, 16 restricted access, 17 unmet expectations regarding weight loss, weight regain after cessation, 18 and particularly high early discontinuation rates among individuals treated for obesity without diabetes

I have been on GLP-1 for 5 weeks and ACE for 1.5 weeks

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