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The activation of the ghrelin receptor leads to an increase in intracellular calcium levels and appetite, which then alerts the pituitary gland to release growth hormone

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Common side effects include injection site irritation, mild headache, and transient flushing

When injectable delivery is the more logical choice: The target is systemic (GH pulse stimulation, tissue repair at non-GI sites, systemic inflammation)

TABLE 8 TMA value in blood of C57Bl/6-Fmo3 em1smoc mice