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In healthy subjects, lixisenatide compared with short-acting insulin increased meal-induced fractional excretion of sodium (absolute change: + 0.25%) but did not affect fasting urinary excretion of other electrolytes or urea
Both patients and doctors need to understand that these drugs also lower cardiovascular disease outcomes that may be even more important than their weight loss effects since cardiovascular disease is the leading cause of death for persons with diabetes or overweight/obesity (evidence already published for Ozempic showing reduction in cardiovascular events, pending for Wegovy and clinical trials are ongoing for Mounjaro). Type 2 diabetes can be managed
Minor side effects rarely require discontinuation
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How Zepbound Works for Weight Loss 3 Mechanisms Zepbound enhances the bodys natural metabolic processes through three primary mechanisms
Talukdar, 2012
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